• 上海博升生物科技有限公司 歡迎您！   郵箱登錄  網站地圖  舊站入口

    產品分類 > 過敏疾病檢測原料 > Recombinant Bla g 2 重組德國小蠊過敏原Bla g2
      • 1

    Recombinant Bla g 2 重組德國小蠊過敏原Bla g2

    產品貨號：RP-BG2-1
    促銷： ￥8720.00
    價格： ￥8720.00

    分享

    250ug
    美國Indoor
    Allergen:rBla g 2 (Blattella germanica allergen 2 )

    Unit:250μg

    Source:P. pastoris (clone NIG rBla g 2, glycosylation site N93Q mutated)

    Mol. Wt:~37 kD

    Purification:Purified from Pichia pastoris culture supernatant by monoclonal antibody affinity chromatography. Purity by silver stained SDS-PAGE > 95%.

    Concentration:

    See product insert. 

    Formulation:

    Preservative and carrier-free in phosphate buffered saline, pH 7.4. Filtered through 0.22 μm filter.

    Storage:Store at -20oC.

    Notes:(1) One glycosylation site was removed in this recombinant leaving two glycosylation sites. The recombinant is glycosylated and has a slightly higher MW than natural. Bla g 2 (36kD).

    (2) This recombinant form was used to determine the crystal structure of Bla g 2.

    Genbank:U28863 Mutation N93Q, substituted cag (Q) for aac (N)

    PDB:1YG9, 2NR6 (with Fab-7C11), X-ray crystal structures

    Product Resources:Recombinant Bla g 2 Certificate of Analysis

    Allergens are provided for research and commercial use in vitro:  not for human in vivo or therapeutic use.

    References:

    1. Arruda LK, Vailes LD, Mann BJ, Shannon J, Fox JW, Vedvick TS, Hayden ML, Chapman MD. Molecular Cloning of a major cockroach (Blatella germanica) allergen, Bla g 2: Sequence homology to the aspartic proteases. J Biol Chem 1995;270:19563-8.

    2. Wünschmann S, Gustchina A, Chapman MD, Pomés A. Cockroach allergen Bla g 2: An unusual aspartic proteinase. J Allergy Clin Immunol 2005;116:140-5.

    3. Gustchina A, Li M, Wünschmann S, Chapman MD, Pomés A, Wodawer A. Crystal structure of cockroach allergen Bla g 2, an unusual zinc binding aspartic protease with a novel mode of self-inhibition. J Mol Biol 2005;348:433-44.

    4. Pomés A, Chapman MD, Vailes LD, Blundell TL, Venugopal D. Cockroach allergen Bla g 2: Structure function and implication for allergic sensitization. Amer J Resp Crit Care Med 2002;165:391-7.

    5. Li M, Gustchina A, Alexandratos J, Wlodawer A, Wünschmann S, Kepley CL, Chapman MD, Pomés A. Crystal structure of a dimerized cockroach allergen Bla g 2 complexed with a monoclonal antibody. J Biol Chem, 2008;283:22806-22814


    上一個： Natural Bla g 2 德國小蠊過敏原Bla g2
    下一個： Bla g 2 ELISA kit (EL-BG2) 德國小蠊過敏原Bla g2檢測試劑盒
    返回
    TOP
    QQ客服
    021-5425 3791
    qrCode
    久久精品网站免费观看_中日韩精品视频在线观看_九九线精品视频在线观看视频_播放