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    產品分類 > 過敏疾病檢測原料 > Recombinant Bla g 4 重組德國小蠊過敏原Bla g4
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    Recombinant Bla g 4 重組德國小蠊過敏原Bla g4

    產品貨號：RP-BG4-1
    促銷： ￥8720.00
    價格： ￥8720.00

    分享

    250ug
    美國Indoor
    Allergen:rBla g 4 (Blattella germanica allergen 4)

    Unit:250μg

    Source:P. pastoris

    Mol. Wt:23kD

    Purification:Purified from Pichia pastoris culture by phenol sepharose and gel filtration chromatography. Purity >95% by SDS-PAGE.

    Concentration:

    See product insert.

    Formulation:

    Preservative and carrier-free in phosphate buffered saline, pH 7.4. Filtered through 0.22 μm filter.

    Storage:Store at -20oC.

    Notes:(1) rBla g 4 is produced in P. pastoris as a glycosylated allergen with MW slightly higher than that predicted for natural Bla g 4 (21kD). (2) Not tested for endotoxin.

    Genbank:U40767

    PDB:3EBk, 3EBW, X-ray crystal structures

    Product Resources:Recombinant Bla g 4 Certificate of Analysis

    Allergens are provided for research and commercial use in vitro:  not for human in vivo or therapeutic use.

    References:


    1. Vailes LD, Kinter MT, Arruda LK, Chapman MD. High level expression of cockroach allergen, Bla g 4 in Pichia pastoris. J Allergy Clin Immunol 1998;101:274-80.

    2. Arruda LK, Vailes LD, Hayden ML, Benjamin DC, Chapman MD. Molecular cloning of cockroach allergen, Bla g 4, identifies ligand binding proteins (or calycins) as a cause of IgE antibody responses. J Biol Chem 1995;270:31196-210.

    3. Arruda LK, Vailes LD, Ferriani VPL, Santos ABR, Pomés A, Chapman MD. The role of cockroach allergens in asthma. J Allergy Clin Immunol 2001;107:419-28.

    4. Fan Y, Gore JC, Redding KO, Vailes LD, Chapman MD, Schal C. Tissue localization and regulation by juvenile hormone of human allergen Bla g 4 from the German cockroach, Blattella germanica (L.). Insect Mol Biol, 2005;14:45-53.

    5. Tan YW, Chan SL, Ong TC, Yit lY, Tiong YS, Chew FT, Sivaraman J, Mok YK. Structures of two major allergens, Bla g 4 and Per a 4, from cockroaches and their IgE binding epitopes. J Biol Chem, 2009;284:3148-3157.


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